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| Project should focus on the generation of software that first of all allows for a rapid assessment of the quality of the sequence data. New ways for mapping short reads to a reference genome should be designed, allowing for more flexible gap options, variable assembling parameters that rely on the local context of the genomic region and iterative read mapping. | Project should focus on the generation of software that first of all allows for a rapid assessment of the quality of the sequence data. New ways for mapping short reads to a reference genome should be designed, allowing for more flexible gap options, variable assembling parameters that rely on the local context of the genomic region and iterative read mapping. | ||
| ==Discussion== | ==Discussion== | ||
| - | nd | + | LF: identifying large structural variations with unfinished genomes is rather difficult. What is possible is to remap the paired-end or better the mate-pair reads and use that information. There are a number of tools able to do that: breakdancer, |
| + | Ken Chen, Aaron Quinlan, gasv@cs.brown.edu, | ||
| + | |||